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A study conducted on patients with PCOS demonstrated significant improvements in BMI, low-density lipoprotein (LDL) cholesterol, and total cholesterol levels following treatment with metformin

Methods: In this cross-sectional study we compared plasma vitamin B12, methylmalonic acid, and homocysteine levels between 50 RA patients treated with methotrexate and folic acid and 49 RA patients using other DMARDs

Alamro AA, Alsulami EA, Almutlaq M, Alghamedi A, Alokail M, Haq SH (2020) Therapeutic potential of vitamin D and curcumin in an in vitro model of Alzheimer disease

Theyre especially beneficial for women with MTHFR gene variants , where the ability to process folic acid from supplements is impaired

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